Nprostate-specific antigen and prostate cancer prediction detection and monitoring pdf

Lilja h, ulmert d, vickers aj prostatespecific antigen. Medical coverage policy prostate specific antigen psa. Electroactive cu2o nanoparticles and ag nanoparticles. Prognostic and predictive biomarkers in prostate cancer. Pdf on may 1, 2008, hans lilja h and others published prostate specific antigen and prostate cancer. Most healthy men have levels under 4 nanograms per milliliter ngml of blood.

The chance of having prostate cancer goes up as the psa level goes up. To delineate how recent findings on prostate specific antigen psa can improve prediction of risk, detection, and prediction of clinical endpoints of prostate cancer pca. An artificial neural network for five different assay systems of prostate specific antigen in prostate cancer diagnostics. Early detection of prostate specific antigen psa could reduce the mortality from prostate cancer. Prostate specific antigen is a substance made by cells in the prostate gland both normal cells and cancer cells. Electroactive nanostructures have attracted much attention due to their excellent electronic conductivity and favorable biological microenvironment. Psa is a member of the kallikreinrelated peptidase family and is secreted by the epithelial cells of the prostate gland psa is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm. Diagnosis is often achieved at an early stage of the disease with prostate biopsy, following a screening test showing elevated serum levels of prostatespecific antigen or a positive digital rectal examination. Early prostatespecific antigen changes and the diagnosis. Prostate specific antigen psa screening and new biomarkers for prostate cancer pca. Despite multiple prospective clinical trials, observational studies, retrospective analyses, and simulation models, intense controversy persists regarding the value of screening for prostate cancer with the prostate specific antigen psa test. Prostate cancer pca is one of the leading causes of cancer death among males, especially in 5 more developed countries.